Why You’ll Love This Casserole
Chicken Bubble Biscuit Bake Casserole is an incredibly comforting dish that makes for a perfect weeknight dinner. This recipe brings together tender chicken, fluffy biscuits, and a creamy sauce, all baked to golden perfection. The flavors meld beautifully, and the dish is a crowd-pleaser that is sure to satisfy even the pickiest of eaters. Not only is it simple to make, but it can also be customized to suit your preferences, making it a versatile addition to your dinner rotation.

This casserole is perfect for using up leftover chicken or rotisserie chicken, making it a great choice for those busy evenings when you need something quick yet delicious. Additionally, with its easy preparation and minimal cleanup, you’ll find that this dish is as practical as it is delectable. So grab your apron, and let’s dive into making this delightful meal!
Ingredients
- 2 cups cooked chicken, shredded
- 1 can (10.5 ounces) cream of chicken soup
- 1 cup sour cream
- 1 cup chicken broth
- 1 cup frozen mixed vegetables (optional)
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon dried thyme
- Salt and pepper to taste
- 1 can (8 ounces) refrigerated biscuit dough
- 1 cup shredded cheddar cheese
Directions
- Preheat the oven to 350°F (175°C).
- In a large mixing bowl, combine the shredded chicken, cream of chicken soup, sour cream, chicken broth, frozen mixed vegetables (if using), garlic powder, onion powder, dried thyme, and salt and pepper. Stir well until all ingredients are evenly mixed.
- Pour the mixture into a greased 9×13-inch casserole dish, spreading it out evenly.
- Open the can of biscuit dough and separate the biscuits. Cut each biscuit into quarters.
- Arrange the biscuit pieces over the chicken mixture in the casserole dish in a single layer.
- Sprinkle the shredded cheddar cheese evenly over the top of the biscuits.
- Bake for 25 to 30 minutes, or until the biscuits are golden brown and fully cooked. You may want to broil it for an additional minute for extra crispiness.
- Let the casserole sit for about 10 minutes before serving to allow it to set slightly.

Tips for the Perfect Chicken Bubble Biscuit Bake
- Use Leftover Chicken: This dish is an excellent way to repurpose leftover chicken or turkey. Just shred it into bite-sized pieces and mix it right into the casserole.
- Add Your Favorite Veggies: Enhance the nutritional value and flavor by adding other vegetables like broccoli, spinach, or bell peppers. Just be sure to pre-cook firmer vegetables.
- Adjust the Seasoning: Feel free to mix up the herbs and spices to suit your palate. Fresh herbs like parsley or basil can be fantastic additions.
- Store Leftovers Properly: Keep any leftovers in an airtight container in the fridge for up to three days. Reheat in the oven or microwave, adding a little bit of broth to keep it moist.
Serving Suggestions
Serve the Chicken Bubble Biscuit Bake Casserole with a fresh garden salad or some steamed vegetables on the side to make it a well-rounded meal. You might also consider pairing it with garlic bread or crusty rolls, which are perfect for soaking up any leftover sauce.
Conclusion
Chicken Bubble Biscuit Bake Casserole is not just a meal; it’s an experience that brings family and friends together around the table. The delightful combination of flavors and textures, along with its ease of preparation, makes this casserole a must-try for anyone looking to streamline their cooking without sacrificing taste. Whether you’re preparing a meal for a busy weeknight or entertaining guests, this casserole is guaranteed to impress and satisfy.
Give this recipe a try today you and your loved ones are sure to love it!

Chicken Bubble Biscuit Bake Casserole
Ingredients
Casserole Base
- 2 cups cooked chicken, shredded Leftover or rotisserie chicken works well.
- 1 can cream of chicken soup (10.5 ounces)
- 1 cup sour cream
- 1 cup chicken broth
- 1 cup frozen mixed vegetables Optional; can include vegetables like broccoli or spinach.
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon dried thyme
- Salt and pepper to taste
Topping
- 1 can refrigerated biscuit dough (8 ounces)
- 1 cup shredded cheddar cheese
Instructions
Preparation
- Preheat the oven to 350°F (175°C).
- In a large mixing bowl, combine the shredded chicken, cream of chicken soup, sour cream, chicken broth, frozen mixed vegetables (if using), garlic powder, onion powder, dried thyme, and salt and pepper. Stir well until all ingredients are evenly mixed.
- Pour the mixture into a greased 9×13-inch casserole dish, spreading it out evenly.
- Open the can of biscuit dough and separate the biscuits. Cut each biscuit into quarters.
- Arrange the biscuit pieces over the chicken mixture in the casserole dish in a single layer.
- Sprinkle the shredded cheddar cheese evenly over the top of the biscuits.
Cooking
- Bake for 25 to 30 minutes, or until the biscuits are golden brown and fully cooked. You may want to broil it for an additional minute for extra crispiness.
- Let the casserole sit for about 10 minutes before serving to allow it to set slightly.